Phosphoryl Guanidines: A New Type of Nucleic Acid Analogues
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چکیده
منابع مشابه
Phosphoryl Guanidines: A New Type of Nucleic Acid Analogues
A new type of nucleic acid analogues with a phosphoryl guanidine group is described. Oxidation of polymer-supported dinucleoside 2-cyanoethyl phosphite by iodine in the presence of 1,1,3,3-tetramethyl guanidine yields a dinucleotide with an internucleoside tetramethyl phosphoryl guanidine (Tmg) group as the main product. The Tmg group is stable under conditions of solid-phase DNA synthesis and ...
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ژورنال
عنوان ژورنال: Acta Naturae
سال: 2014
ISSN: 2075-8251
DOI: 10.32607/20758251-2014-6-4-116-118